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By Emily Greifeld

Expanding into the U.S. is a significant step for French biotech companies seeking to scale operations, attract investment, and gain access to the world’s most advanced life sciences market. However, breaking into the U.S. requires more than just a strategic location and regulatory compliance—it requires a targeted, high-impact communications strategy to establish credibility, secure partnerships, and build visibility in a highly competitive landscape.

A Multi-Layered Communications Strategy for U.S. Expansion

To stand out in the U.S. biotech sector, French companies must execute a strategic and phased communications plan. Simply setting up an office or attending an event won’t generate traction. Instead, companies must own their narrative, leverage media exposure, and create thought leadership opportunities that position them as a credible force in the industry.

A well-executed press and media relations strategy is one of the fastest ways to gain credibility in a new market. The first step is to announce the expansion with a carefully crafted press release, ensuring it reaches top biotech, healthcare, and business publications. Beyond a general announcement, targeted media pitching to journalists at healthcare and biotech outlets can help secure exclusive interviews or in-depth stories. Additionally, if a company is expanding into a specific U.S. city, securing coverage in local business media, such as the Boston Business Journal or San Francisco Chronicle, can boost awareness within the regional industry ecosystem.

While earned media establishes credibility, thought leadership initiatives elevate biotech executives and position them as industry voices. Executives should pursue bylined articles in respected industry media, such as Life Science Leader, Forbes Healthcare, and STAT First Opinion, to share insights on biotech innovations, regulatory challenges, and scientific breakthroughs. Securing speaking opportunities at major industry events, including BIO International, J.P. Morgan Healthcare Conference, and Biotech Week Boston, will reinforce credibility and create networking opportunities with potential investors and partners. Additionally, executives should use LinkedIn and X strategically, posting commentary on industry trends, engaging with U.S. biotech influencers, and amplifying media coverage to build their professional presence.

Beyond media and thought leadership, direct engagement with investors and strategic partners is crucial for market entry. Organizing exclusive investor briefings in biotech hubs like Boston, New York, and San Diego allows companies to introduce their business model and scientific breakthroughs directly to U.S. investors. Additionally, participating in well-regarded accelerator programs, such as IndieBio, JLABS (Johnson & Johnson’s incubator), and MassChallenge HealthTech, provides access to funding, mentorship, and business development opportunities. Joining industry trade associations, including BIO (Biotechnology Innovation Organization), MassBio, and Biocom California, also opens doors to partnerships and valuable regulatory insights.

A strong digital marketing and social media strategy complements traditional media outreach and direct engagement. French biotech companies should ensure their website is localized for the U.S. audience, incorporating FDA regulatory language, U.S. case studies, and a dedicated landing page for American investors and customers. Maintaining an active presence on LinkedIn and Twitter (X) is essential for biotech companies looking to build relationships with media, investors, and industry professionals. Additionally, targeted digital advertising, such as LinkedIn ads and Google Ads, can help companies reach biotech professionals, investors, and industry decision-makers in key U.S. markets.

Where to Land: East Coast vs. West Coast?

Choosing the right geographic entry point depends on a biotech company’s goals and industry focus.

The East Coast—particularly Boston and New York—remains a powerhouse for biotech and pharmaceutical collaborations. Boston is widely regarded as the global epicenter of biotech and life sciences, thanks to its world-class research institutions, including MIT and Harvard, and its thriving network of venture capital firms, incubators, and pharmaceutical companies. The city is home to MassBio, which offers extensive support for biotech startups looking to establish a foothold in the U.S. market. New York City has a rapidly growing biotech sector fueled by accelerators like JLABS NYC and increasing investments in life sciences infrastructure. Companies looking to raise capital, establish pharma partnerships, or collaborate on clinical trials will find the East Coast an ideal starting point.

The West Coast, particularly the San Francisco Bay Area and San Diego, offers a startup-friendly environment with close proximity to venture capital networks and emerging biotech technologies. The Bay Area, deeply intertwined with Silicon Valley’s innovation culture, is a hub for biotech-AI, synthetic biology, and health tech companies that require tech-driven innovation. San Diego, home to institutions like the Scripps Research Institute and UC San Diego, has a strong reputation for life sciences and biotech research, making it an attractive location for companies focused on drug discovery and clinical trials.

Beyond the coasts, emerging hubs like Houston’s Texas Medical Center—the world’s largest medical complex—offer opportunities for biotech companies interested in clinical trials and hospital partnerships. Similarly, the Research Triangle in North Carolina (Raleigh-Durham) provides a cost-effective alternative with strong biotech research institutions, including Duke, UNC, and NC State.

Final Takeaways for French Biotech Companies

Expanding into the U.S. is a complex but highly rewarding endeavor for French biotech companies. The key to success lies in a strong communications strategy that builds credibility, a targeted geographic approach aligned with the company’s biotech niche, and a well-executed investor and partnership strategy to fuel U.S. growth.

By proactively shaping their narrative, securing visibility, and strategically engaging investors, French biotech firms can successfully integrate into the U.S. ecosystem and thrive in one of the most competitive biotech markets in the world.